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In 1772, nitrous oxide, also known as laughing gas, was discovered. It has a clear odor and taste that is pleasant and sweetish. Inhaling small amounts produces a euphoric effect, while larger amounts produce an anesthetic effect. It was quickly adopted and is still widely used as a safe way to make dental procedures more bearable. By the 1880s, women, including Queen Victoria, use it for pain relief during childbirth.

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Nitrous oxide, which works on some of the same pathways as ketamine, could be an effective treatment for severe treatment-resistant depression. The nitrous treatment is similar to a ketamine treatment in that it is administer for an hour while resting in a comfortable chair, but it uses a soft mask to deliver the gas mixture instead of an IV, and it produces fewer visual and sensation hallucinations than a ketamine infusion.

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A cream battery charger is a steel cylindrical tube or cartridge filled with laughing gas that is used as a whipping agent in whipped cream dispensers. It contains laughing gas, a commonly prescribed and over-the-counter medication used to alleviate labor pain, anxiety, and stress. Despite the fact that cream battery charger is commonly used as a whipping agent, some people use it as a recreational drug due to its high Laughing gas content. Chargers for cream.

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